ABSTRACT
Objective:To investigate the clinical effect of autologous nano-fat injection to correct upper eyelid depression.Methods:From March 2016 to March 2020, a total of 191 eyes were treated in 110 patients with upper eyelid depression, including 81 cases on both sides and 29 cases on one side. The fat was obtained by negative pressure liposuction from the thigh. After the nano treatment, the obtained nano fat was injected into the subcutaneous layer, ROOF layer and orbital septum evenly with multi-tunnel without tension.Results:Among 110 patients, 1-2 ml of nano-fat was filled to the upper eyelid unilaterally, with an average of 1.5 ml. 95 patients were followed up for 2-24 months, with average 6 months. After one injection, the depression of the upper eyelid was significantly improved in all patients, and the correction of the depression of the upper eyelid was insufficient in 28 patients. After 3 months, autologous nano fat filling was performed again, and the results were satisfactory. Temporary ptosis occurred in 5 patients and recovered naturally after 3-6 months. Local ecchymosis and swelling were observed in 12 patients, and resolved spontaneously within 7-14 days. No infection, nodules or other complications occurred in all the patients.Conclusions:Nano-fat is a safe and effective method, which can effectively fill the orbital depression area and correct the depression of upper eyelid, with less adverse reactions.